Moss Lab Research
Identifying molecular, cellular and systems mechanisms driving pathogenesis of the most common inherited peripheral neuropathy, Charcot-Marie-Tooth disease, with the goal of facilitating therapy development for this debilitating disease.
Harnessing the Power of Advanced Animal Models to Accelerate Discoveries
We utilize advanced animal models, including conditional mouse models, to understand the phathophysiology of Charcot-Marie-Tooth disease and to identify systems mechanisms driving their pathogenesis.
Leveraging the Team Science Environment at the University of Missouri
The Moss lab is part of the NextGen Neuroscience Group which is a vibrant and collaborative group that spans the entire nervous system but with a special focus on neuromuscular research.
Employing Cutting-Edge Microscopy Techniques to Dissect Disease Mechanisms
We aim to identify molecular and cellular mechanisms causing Charcot-Marie-Tooth disease to understand disease pathogenesis and reveal targets and approaches for developing therapeutics.
Embracing Diverse Skillsets and the Bench to Bedside Approach to Science
We take advantage of the abundant basic, translational, and clinical neuromuscular expertise at NextGen and throughout the University of Missouri to push the boundaries of our research and work towards translational studies.